SOT 2021 - Poster Presentations and Special Events

SOT Annual Meeting and ToxExpo Virtual Event 2021

Thank you for visiting us at the SOT Annual Meeting and ToxExpo Virtual Event 2021. The following presentations and events have been contributed and are available for download below.

Please note that registered attendees of the Virtual 2021 SOT Annual Meeting and ToxExpo have access to all presentations at the SOT 2021 event platform until May 31, 2021.

Poster Presentations

  • Representations of liver toxicity knowledge by chemotypes based on ontology approach to support biological & chemical grouping in chemical safety assessment

    J. Firman1, T. Magdziarz2, B. Bienfait2, M. Cronin1, D. Ebbrell1, S. Enoch1, B. Hobocienski3, J. Madden1, A. Mostrag-Szlichtyng3, J. Rathman3, V. Ribeiro3, M. Vinken4, and C. Yang2,3

    1Liverpool John Moores University, Liverpool, United Kingdom; 2MN-AM GmbH, Nuremberg, Germany; 3MN-AM LLC, Columbus, OH; and 4Vrije Universiteit Brussel, Brussels, Belgium

    Poster Board P295, Abstract 2557

    Monday, March 22, 2021

    Registered attendees of SOT 2021 can access this presentation at the SOT 2021 Virtual Event pages

     

  • A Case Study to Leverage Public and Commercial Resources to Improve In Silico Chemical Safety Assessment

    A. Mostrag-Szlichtyng1, K. Arvidson2, M. Cronin3, D. Ebbrell3, S. Enoch3, J. Firman3, J. Madden3, J. Marusczyk4, P. Volarath2, J. Rathman1, C. Schwab4, and C. Yang1,4

    1MN-AM, Columbus, OH, USA, 2US FDA/CFSAN, College Park, MD, USA 3Liverpool John Moores University, Liverpool, UK, and 4MN-AM, Nuremberg, Germany

    Poster Board P220, Abstract 2754

    Tuesday, March 23, 2021

     

  • Estimating EC3 (Effective Concentration for a Stimulation Index of Three) Confidence Bounds and Uncertainties for Skin Sensitization Based on Structure Similarity and Assay Profiles

    J. Rathman1, C. Yang1,2, M. Cronin3, and S. Enoch3

    1MN-AM, Columbus, OH, USA 2MN-AM, Nuremberg, Germany, and 3Liverpool John Moores University, Liverpool, UK

    Poster Board P264, Abstract 2798

    Tuesday, March 23, 2021

     

  • New Public CSRML-Based Structure-Fingerprint Method for Profiling and Categorizing PFAS Structures for Modeling and Read-Across

    A.M. Richard1, R. Lougee2, G. Patlewicz1, C. Grulke1, A. Williams1, C. Yang3, J. Rathman4, and T. Magdziarz3

    1US EPA, Research Triangle Park, NC, USA, 2Oak Ridge Institute for Science and Education, Oak Ridge, TN, USA, 3MN-AM, Nuremberg, Germany, and 4MN-AM, Columbus, OH, USA

    Poster Board P303, Abstract 2565

    Monday, March 22, 2021

    Registered attendees of SOT 2021 can access this presentation at the SOT 2021 Virtual Event pages

     

Oral Presentations

  • A New Paradigm in Threshold of Toxicological Concern Transforming Cramer Class Approaches to Chemotype Grouping Based on Chemoinformatics Analysis of a Highly Curated Database

    Chihae Yang

    MN-AM, Nuremberg, Germany and Columbus, OH, USA

    Workshop Session 1234

    Monday, March 22, 2021

    Registered attendees of SOT 2021 can access this presentation at the SOT 2021 Virtual Event pages

     

  • The New Cancer Potency (Updated CPDB) Database for TTC

    M.T. Cronin1, J.W. Firman1, J. Liu2, A. Mostrag-Szlichtyng2, K.R. Przybylak1, and A. Tarkhov3

    1Liverpool John Moores University, Liverpool, UK, 2Altamira LLC, Columbus, OH, USA, and 3Molecular Networks GmbH, Nuremberg, Germany

    Workshop Session 1232

    Monday, March 22, 2021

    Registered attendees of SOT 2021 can access this presentation at the SOT 2021 Virtual Event pages

     

Special Events

  • MN-AM, Molecular Networks & Altamira: Novel Chemoinformatics Platform ChemTunes·ToxGPS® and Its Public Version COSMOS Next Generation

    MN-AM (Molecular Networks & Altamira) presents an innovative chemoinformatics approach to estimate NOAEL confidence bounds for a target based on experimental NOAEL of compounds selected based on mode-of-action categories and analog quality (structure- and property-based similarity). The new COSMOS Next Generation public data and knowledgebase system will also be presented in this session.

    Tuesday, March 23, 2021

    Download invitation