Visit us at SOT Annual Meeting and ToxExpo 2020

MN-AM.com is attending the upcoming 59th Annual Meeting and ToxExpo of the Society of Toxicology in Anaheim, CA, USA, from March 15 to 19, 2020. We would like to invite you to visit our booth no. 776 at the ToxExpo.

We will demonstrate our suite of software tools and applications in the area of computational toxicology. We are available to answer any questions regarding our technology and will be glad to help you finding the right solution for your challenges.

In addition, please find below a list of scientific presentation related to our technology that will be given in the technical sessions at the 2020 SOT Annual Meeting.

We are looking forward to meeting you in Anaheim.

Poster Presentations

  • Comparison of NOAEL, ETD10, and BMDL10 Values for Nongenotoxic Carcinogens: Which Point of Departure Is Most Sensitive?

    M. Batke1, H.M. Hollnagel2, M.T.D. Cronin3, C. Yang4, J.F. Rathman5 and S.E. Escher1

    1Fraunhofer Institute for Toxicology and Experimental Medicine, Hanover, Germany; 2Dow Europe GmbH, Horgen, Switzerland; 3Liverpool John Moores University, Liverpool, United Kingdom; 4Molecular Networks GmbH, Nuremberg, Germany; 5Altamira LLC, Columbus OH, Columbus, OH, USA.

    Poster Board P396, Abstract 1329

    Monday, March 16, 2:15pm - 4:30pm

    CC Exhibit Hall, Poster Session: Carcinogenicity

     

  • Role of a Chemoinformatics Platform in Industry Research Programs and Risk Assessments for Cosmetics Ingredients

    M.T.D. Cronin1, M. Dent2, B. Desprez3, A. Detroyer4, J. Fisher5, S. Gutsell2 M. Klaric3, C. Mahony6, J. Marusczyk7, G. Ouedraogo4, A. Tarkhov7, E. Vandenbossche2 and C. Yang7,8

    1Liverpool John Moores University, Liverpool, United Kingdom; 2Unilever Safety and Environmental Assurance Centre, Sharnbrook, United Kingdom; 3Cosmetics Europe, Brussels, Belgium; 4L’Oréal, Paris, France; 5Procter & Gamble, Cincinnati, OH; 6Procter & Gamble, Egham, United Kingdom; 7Molecular Networks GmbH, Nuremberg, Germany; 8Altamira LLC, Columbus, OH, USA.

    Poster Board P389, Abstract 2055

    Tuesday, March 17, 9:00am - 10:45am

    CC Exhibit Hall, Poster Session: Computational Toxicology I

     

  • Combining Evidence to Assess Mutagenicity of Impurities by Supplementing QSAR, Rule-Based, and Read-Across Predictions with Expert Opinions

    A. Mostrag-Szlichtyng1, B. Bienfait2, E. Fioravanzo3, T. Magdziarz2, J. Marusczyk2, J. Park4 J.F. Rathman1,5, P. Russel3, O. Sacher2, C.H. Schwab2, A. Tarkhov2 and C. Yang1,2,4

    1MN-AM, Columbus, OH, USA; 2MN-AM, Nuremberg, Germany; 3ToxNavigation Ltd., East Molesey, United Kingdom; 4MN-AM, Seoul, Korea, Republic of; 5Ohio State University, Columbus, OH, USA.

    Poster Board P590, Abstract 2959

    Wednesday, March 18, 2:15pm - 4:30pm

    CC Exhibit Hall, Poster Session: Computational Toxicology II

     

  • Weight of Evidence Assessment of Genotoxicity Based on a Battery of Genetic Toxicity Assays: Improvement of Decision Making for Genotoxic Carcinogens

    J.F. Rathman1,2, M.T.D. Cronin3, D. Ebbrell3, S.E. Escher4, A. Mostrag-Szlichtyng1 and C. Yang7,8

    1MN-AM, Columbus, OH, USA; 1The Ohio State University, Columbus, OH, USA; 3Liverpool John Moores University, Liverpool, United Kingdom; 4Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany; 5MN-AM, Nuremberg, Germany.

    Poster Board P606, Abstract 2975

    Wednesday, March 18, 2:15pm - 4:30pm

    CC Exhibit Hall, Poster Session: Computational Toxicology II

     

  • A Novel Method for Estimating NOAEL Bounds by Chemoinformatics and Well-Curated Database

    C. Yang1, J.F. Rathman2, A. Mostrag-Szlichtyng2, 3, T. Magdzirz1 S. Kulkarni4 and T.S. Barton-Maclaren4

    1MN-AM, Nuremberg, Germany; 2MN-AM, Columbus, OH, USA; 3Health Canada, Ottawa, ON, Canada.

    Poster Board P119, Abstract 3306

    Thursday, March 19, 8:30am - 11:30am

    CC Hall C, Poster Session: Late-Breaking 1: Nanotoxicology; Computational; Modeling; Systems Biology; Emerging Technologies

     

  • A Cheminformatics Read-Across Workflow to Assess the Genotoxicity and the Skin Sensitization of a UVCB Substance with a Constituent-Based Approach

    E. Fioravanzo1, T. Magdziarz2, J. Marusczyk2, A. Mostrag-Szlichtyng3, J.F. Rathman3,4 P. Russel1, O. Sacher2, C.H. Schwab2and C. Yang2,3

    1ToxNavigation Ltd., East Molesey, United Kingdom; 2Molecular Networks GmbH, Nürnberg, Germany; 2MN-AM, Nuremberg, Germany; 3Altamira LLC, Columbus, OH, USA; 4Ohio State University, Columbus, OH, USA.

    Poster Board P123, Abstract 3310

    Thursday, March 19, 8:30am - 11:30am

    CC Hall C, Poster Session: Late-Breaking 1: Nanotoxicology; Computational; Modeling; Systems Biology; Emerging Technologies

     

  • Skin Permeability Profiler: The First Step in the ChemTunes·ToxGPS® "Skin Suite" for Comprehensive Assessment of Dermal Toxicity

    B. Heldreth1,J. Zhu1, C. Yang2, J.F. Rathman3,4, A. Mostrag-Szlichtyng3 and T. Magdziarz3

    1Cosmetic Ingredient Review, Washington, DC, USA; 2MN-AM, Nuremberg, Germany; 3MN-AM, Columbus, OH, USA.

    Poster Board P207, Abstract 3394

    Thursday, March 19, 8:30am - 11:30am

    CC Hall C, Poster Session: Late-Breaking 1: Nanotoxicology; Computational; Modeling; Systems Biology; Emerging Technologies

     

Special Events

  • MN-AM, Molecular Networks & Altamira - COSMOS NG / ToxGPS Reception: Toxicity Data and Workflows to Improve Chemical Safety and Risk Assessment

    Anaheim Marriott, 700 West Convention Way, Anaheim, CA 92802, Orange County Ballroom 4 (ground level)

    Monday, March 16, 5:00pm - 7:00pm

     

  • MN-AM, Molecular Networks & Altamira: Novel Method for Estimating NOAEL Confidence Bounds with ChemTunes·ToxGPS®

    MN-AM (Molecular Networks & Altamira) presents a new and innovative methodology to estimate the no-observed-adverse-effect-level (NOAEL) confidence bounds for target compounds in read-across based on NOAEL values of analogs including analog quality, mode of action (MoA) categories, and uncertainty assessment.

    Convention Center, Room 205A

    Tuesday, March 17, 4:30pm- 5:30pm